Drug repurposing is a strategy focused on identifying new therapeutic applications for existing drugs. This approach may significantly shorten the time needed to develop new therapies while reducing the costs of clinical research. However, the authors of a recent publication emphasize that studies involving drugs used for new indications require a specific methodological and ethical framework. The main challenges include intellectual property issues, limited data availability, and the widespread use of off-label therapies. Despite these barriers, drug repurposing is currently considered one of the most promising directions in modern pharmacotherapy.
Gordon, S., Klas, K., & Waligora, M. (2026). Factors to consider when designing clinical trials for repurposed drugs. Expert Review of Clinical Pharmacology, 1–11. https://doi.org/10.1080/17512433.2026.2671276